KANSAS CITY, Mo. – St. Francis (Ill.) opens the season at No. 1 in the Coaches’ Preseason Top 25 Poll after winning the 2020 national title.
Dordt starts the season ranked #6, while Morningside received votes.
| RANK | LAST TIME | SCHOOL [FIRST-PLACE VOTES] | POINTS |
| 1 | 1 | St. Francis (Ill.) [20] | 560 |
| 2 | 3 | Taylor (Ind.) | 530 |
| 3 | 2 | College of Idaho | 523 |
| 4 | 7 | Milligan (Tenn.) | 512 |
| 5 | 5 | Indiana Wesleyan | 488 |
| 6 | 8 | Dordt (Iowa) | 466 |
| 7 | 9 | Aquinas (Mich.) | 451 |
| 8 | 10 | Saint Mary (Kan.) | 397 |
| 9 | 11 | Montreat (N.C.) | 394 |
| 10 | 12 | Huntington (Ind.) | 391 |
| 11 | 13 | Lewis-Clark State (Idaho) | 377 |
| 12 | 4 | Embry-Riddle (Ariz.) | 353 |
| 13 | 15 | Oregon Tech | 334 |
| 14 | 16 | Cornerstone (Mich.) | 319 |
| 15 | 17 | The Master’s (Calif.) | 298 |
| 16 | 23 | Saint Francis (Ind.) | 280 |
| 17 | 19 | Carroll (Mont.) | 270 |
| 18 | NR | Southern Oregon | 242 |
| 19 | 18 | Dalton State (Ga.) | 207 |
| 20 | 22 | Southeastern (Fla.) | 193 |
| 21 | 20 | Cumberlands (Ky.) | 191 |
| 22 | 25 | Olivet Nazarene (Ill.) | 188 |
| 23 | 6 | Oklahoma City | 171 |
| 24 | 21 | Northwest (Wash.) | 163 |
| 25 | NR | Baker (Kan.) | 131 |
Receiving Votes: William Woods (Mo.) 102, Morningside (Iowa) 77, Grace (Ind.) 74, Columbia (Mo.) 44, Westmont (Calif.) 40, MidAmerica Nazarene (Kan.) 33, Indiana Tech 33, Friends (Kan.) 27, Montana Western 24, Wayland Baptist (Texas), 10, SCAD Savannah (Ga.) 9, Benedictine (Kan.) 8, Eastern Oregon 7, Shawnee State (Ohio) 6
