Iowa State coach Matt Campbell says he is not surprised by the turnaround at Kansas.
The Jayhawks are off to a 4-0 start, the most wins by a KU team since the 2009 squad finished 5-7.
The Jayhawks started 1-8 a year ago under coach Lance Leipold before posting a stunning victory at Texas late in the season.
Dual threat quarterback Jalon Daniels has 11 touchdown passes for the Jayhawks and has rushed for four others.
Daniels leads a Kansas offense that is averaging 47 points per game.
Campbell says the Kansas run game will be a challenge for the Cyclone defense.